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Table 3 Characteristics of individuals enrolled in this study

From: Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia

   c.709-1G > A mutation carriers
  Control n = 10 Asymptomatic n = 12 FTLD patients n = 7
Age (years) 51.8 ± 4.3 52.8 ± 4.3 65.3 ± 2.3
Sex, female, % (n) 50 % (5) 50 % (6) 100 % (7)
Age at onset - - 61 ± 0.6
Phenotype Asymptomatic Asymptomatic FTD-bv; CBS
Family history, % (n) 70 % (7) 54.5 % (6) 57.1 % (4)
  1. Control: Individuals without sing of neurological degeneration; c.709-1G > A: GRN mutation carriers; n: number of subjects. Values are expressed as mean ± SEM. CBS Cortico-basal syndrome, FTD-bv Frontotemporal dementia (behavior)