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Table 1 Specificity and sensitivity of the screening assay based upon an SSMD threshold of < -0.5

From: ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis

  Replicate 1 Replicate 2
Sensitivity in percentage 94.8 % ± 9.85 96.6 % ± 8.8
Specificity in percentage 85.2 % ± 13.2 93.2 % ± 9.0
  1. The assay statistics from 40 plates in each replicate including 12 positive control (riluzole) and 12 negative control wells. The false positive and false negative numbers were utilized to calculate the specificity and sensitivity of the assay expressed as percentage mean and standard deviation
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Molecular Neurodegeneration

ISSN: 1750-1326