Fig. 9
From: The release and trans-synaptic transmission of Tau via exosomes
Diagram of exosome-mediated Tau transmission. (1) When Tau-containing exosomes are released into extracellular space, they can be taken up by neurons. (2) The internalized exosomes undergo axonal transport and finally are released at pre-synaptic terminals. (3) The released exosomes are taken up by the synaptically connected neurons, resulting in the distribution of Tau in these recipient cells