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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Tdp-43 cryptic exons are highly variable between cell types

Fig. 3

Muscle-specific cryptic exons (MLC-Cre;Tardbp F/F knockout mice). (a) Visual examples of muscle-specific cryptic exons (Sh3bgr, Tns1). (b) Muscle-specific cryptic exons are flanked by UG repeats that are present upstream, downstream or within the cryptic exon sequence itself. (c and d) RT-PCR validation of cryptic exons (red arrows) in RNA extracted from quadriceps of 2 month old MLC-Cre;Tardbp F/F mice. Refer to Additional file 2 for a complete list of cryptic exons

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