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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Quantitative proteomic analysis of Parkin substrates in Drosophila neurons

Fig. 4

Distribution of ubiquitinated proteins according to Parkin catalytic activity. Volcano plot showing the outcome of the ParkinWT vs ParkinLD T-test performed with Perseus. Proteins are distributed along x axis by fold change of LFQ intensity and y axis by p-value. Proteins in bold, represent the most robust Parkin responders (35 enriched and 2 reduced - Table 1) whose LFQ change at the protein level is also coherently detected at the peptide level (Additional file 5: Figure S5)

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