DcR3 restored the pre-synapse marker expression in APP mice. a Representative immunofluorescence synaptophysin images in the hippocampus. MF: mossy fiber; DG: dentate gyrus. Scale bar: 100 μm.
b Quantification of synaptophysin intensity in CA3-mossy fibers, CA1, and the DG regions. N = 7-14 slices from at least 3 mice per genotype. c Representative Western blot imaging of PSD95 among four genotypes of mice and d averaged intensity of PSD95. N = 5 mice per genotype. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001