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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model

Fig. 4

DcR3 reversed amyloid pathology in APP mice. a Representative thioflavin-S staining images in coronal brain sections from 12-month-old APP and APP/DcR3 mice. Scale bar: 100 μm. b Quantification of the percentage of area covered by amyloid plaques in the hippocampi of APP and APP/DcR3 mice. N = 24–34 slices from 4–6 mice per genotype. c, d The hippocampal levels of guanidine soluble c total Aβ1-x and d Aβ1-42 in APP and APP/DcR3 mice were measured via ELISA. N = 6 mice per genotype. **P ≤ 0.01 versus APP mice

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