Fig. 3

TREM2 is expressed in many immune cells, and is localized to microglia in the CNS. TREM2 expression has been assessed in a variety of human and mouse cell types. These data represent TREM2 expression in these cells under homeostatic conditions, though, as discussed in the next section, TREM2 expression can change in the contexts of inflammation or pathology. References shown in green are supportive of TREM2 expression in the cell type listed while those in red did not detect TREM2 expression using the listed method of detection. References in yellow provide evidence of expression, but at low levels or in a small percentage of cells assayed. The graph represents the cell types in which TREM2 expression has been examined at a size relative to the number of studies and methods used to detect TREM2 expression in that cell type. They are graphed along the y-axis according to the percentage of these findings which support TREM2 expression on these cells [11, 19, 25, 26, 85, 101, 116, 126, 128, 130, 134,135,136,137, 139,140,141,142,143, 145, 150,151,152,153,154,155,156,157,158,159,160, 162, 164, 165, 216, 219, 200]