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Fig. 8 | Molecular Neurodegeneration

Fig. 8

From: Hexokinases link DJ-1 to the PINK1/parkin pathway

Fig. 8

Cytosolic accumulation of HK2 inhibits the PINK1/parkin pathway. a-c HK2 was dissociated from mitochondria in HeLa cells using a peptide derived from the VDAC-binding domain of HK2 (HK2VBD) for 30 min prior to a 1-h treatment with 5 μM CCCP. Images and quantification are displayed as in Fig. 6

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Molecular Neurodegeneration

ISSN: 1750-1326