Fig. 5

Class II Tau pathology. Three different genetic backgrounds have been studied with AT8 antibody as per Fig. 4. In distinction to class I there is staining in the cortex corresponding to NFT’s and GFT’s (a, h, o, b, i, p) but like class I has staining in hippocampus (panels c, j, q, d, k and r) and caudate putamen (panels e, l, s, f, m, t), with the pons being spared (g, n, u). Scale bar = 500 μm for panels c, j and q. Scale bar = 250 μm for panels a, e, g, h, l, n, o, s and u. Scale bar = 50 μm for panels b, d, f, i, k, m, p, r and t