Fig. 7

Class IV Tau pathology. Different genetic backgrounds and anatomical structures have been studied with AT8 antibody as per Fig. 4. In contrast to classes I-III, immunostaining is restricted to the pons (d, e, i, j, n, o). Scale bar = 500 μm for panels b, g, and l. Scale bar = 250 μm for panels a, c, d, f, h, i, k, m, and n. Scale bar = 50 μm for panels e, j, and o. Cells presented in panel j exhibit vacuoles