Class V Tau pathology. Class V comprised the rarest class of pathology. Three out of four occurrences were in the 129/SvEvTac background and a single mouse from this background is represented with AT8 or MC1 staining. In contrast to class IV, immunostaining encompasses the hippocampus (b, c, h, i). Scale bar = 500 μm for panels b, and h. Scale bar = 250 μm for panels a, d, e, g, j, and k. Scale bar = 50 μm for panels c, f, i, and l.