Fig. 3

Identified small molecular IRE inhibitors that modulate the translation of α-Syn and APP. a Identified IRE inhibitors with a capacity to inhibit α-Syn translation. b Identified IRE inhibitors with a capacity to inhibit APP translation. c Identified IRE inhibitors with a capacity to inhibit both α-Syn and APP translation. d Table 1. Summary of IRE inhibitors potential for AD and PD therapies