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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

Fig. 4

Top 10 enriched Gene Ontology (GO) biological process pathways. Pathway enrichment was performed on striatal DEGs downregulated in vehicle-treated YAC128 mice (top panel), striatal DEGs upregulated after treatment with 10 mg/kg pridopidine in YAC128 (second panel), striatal DEGs upregulated after treatment with 30 mg/kg pridopidine in YAC128 (third panel), and striatal DEGs upregulated after treatment with 10 mg/kg pridopidine in WT (second panel)

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Molecular Neurodegeneration

ISSN: 1750-1326