Fig. 1
From: Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain
Analysis of GRS vs. cognitive decline slopes (n = 1601). Two-sided uncorrected P-values derived from robust regression are shown within tiles. Models co-varied for age at initial assessment, sex, years of education, and three EIGENSTRAT principal components. The color scale indicates magnitude and direction of the effect T-statistic. *significant after FDR correction (PFDR < 0.05)