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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Peripheral immune system in aging and Alzheimer’s disease

Fig. 1

Multifactorial systemic changes are associated with chronological aging and linked to diminished health status. Peripheral aging is promoted by inflammaging, immune cell skewing, senescence, and depletion of youth protective factors. The broad outcome of aging includes increased incidences of infection, autoimmune diseases, and decline of memory and cognitive functions.

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