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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Fig. 2

Genome-wide transcriptome analysis of acutely isolated rTg4510 microglia. a. Principal component analysis (PCA) of all 18,588 transcripts from 28 samples. Plot shows three-dimensional comparison of transcripts in four age groups and two genotypes of microglia cells. Data were transformed by logarithm of base 2. b. Heat map display of the clustering analysis result of all 18,588 transcripts. All data on logarithm of base 2 from 28 samples and hierarchical analysis was carried out in statistical software JMP

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