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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model

Fig. 3

Z-score values of connections of hippocampus to cortical nodes and to nodes of the default mode network. In the control group, the changes between the two time points (baseline; doxycycline treatment for 8 weeks) remain rather small with the exception of some nodes of the DMN. In the transgenic groups, the z-score values at baseline are all only approximately half as strong as for the control group. Upon doxycycline treatment, those z-score values all closely approximate those of the control group

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