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Fig. 9 | Molecular Neurodegeneration

Fig. 9

From: Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

Fig. 9

CaMKII phosphorylation is increased in the synapses of mice treated ICV with NSC-exo. NSC-exo, MN-exo or PBS (vehicle) were injected ICV into adult wild type mice 24 h before euthanasia. Synaptosomes were isolated from the hippocampus and analyzed by western blotting for the expression of total and phosphorylated Ca2+/calmodulin-dependent kinase II (CaMKII) (a). Band intensities were quantified using ImageJ software and normalized to β-actin (b). N = 4 mice/group. ANOVA (F = 11.83) followed by Tukey’s multiple comparisons test

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Molecular Neurodegeneration

ISSN: 1750-1326