Table 1 Comorbidities in 1153 Patients with Pathologic Diagnosis of AD. The majority of AD cases were observed to have pathologic comorbidities as observed in the Mayo Clinic Brain Bank 2007–2016. Plus sign (+) in the column on pathological diagnosis of AD indicates additional pathologies beyond the primary and secondary diagnoses listed. Bold indicates significance from the pure AD cases (Student t-Test, p < 0.01)
From: The neuropathological diagnosis of Alzheimer’s disease
Pathological Dx | Cases (n) | Age (yr) | Brain (g) | Braak | Thal |
|---|---|---|---|---|---|
AD | 243 | 76.5 ± 10.8 | 1077 ± 159 | 5.5 ± 0.7 | 4.7 ± 0.6 |
AD/LBD | 175 | 76.0 ± 10.2 | 1053 ± 151 | 5.6 ± 0.6 | 4.8 ± 0.6 |
AD/LBD+ | 206 | 81.8 ± 9.3 | 1025 ± 170 | 5.6 ± 0.6 | 4.8 ± 0.5 |
AD/Vas | 113 | 84.5 ± 7.9 | 1070 ± 164 | 5.3 ± 0.8 | 4.6 ± 0.8 |
AD/Vas+ | 77 | 86.0 ± 6.4 | 1043 ± 142 | 5.3 ± 0.7 | 4.8 ± 0.6 |
AD/CAA | 42 | 76.1 ± 11.6 | 1089 ± 163 | 5.6 ± 0.6 | 4.6 ± 0.6 |
AD/CAA+ | 110 | 80.1 ± 9.0 | 1086 ± 163 | 5.6 ± 0.6 | 4.7 ± 0.7 |
AD/HpScl | 27 | 86.0 ± 6.9 | 1088 ± 158 | 5.4 ± 0.7 | 5.0 ± 0.0 |
AD/HpScl+ | 51 | 87.8 ± 6.9 | 1012 ± 174 | 5.4 ± 0.7 | 4.8 ± 0.6 |
AD/Other | 59 | 79.3 ± 10.9 | 1044 ± 164 | 5.4 ± 0.8 | 4.7 ± 0.7 |
AD/Other+ | 50 | 81.9 ± 11.2 | 1019 ± 186 | 5.3 ± 0.8 | 4.5 ± 0.8 |