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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

Fig. 2

Human APOE is expressed in astrocytes in APOE-KI mice. a Brain sections from APOE-KI mice were co-stained for nuclei (DAPI), apoE, and GFAP. Multiple foci of ApoE/GFAP co-localization can be seen at high magnification (bottom panels). b Brain sections from APOE-KI mice were co-stained for nuclei (DAPI), apoE, and IBA1. No overlap of apoE and IBA1 staining was observed. Scale bars = 200 μm (top panels) and 50 μm (bottom panels). Images are from E4F mice, and are representative of at least 3 random cortical areas from 3 biological replicates. There were no appreciable qualitative differences between E2F, E3F, and E4F samples

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Molecular Neurodegeneration

ISSN: 1750-1326