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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Application of CRISPR genetic screens to investigate neurological diseases

Fig. 4

Key considerations in choosing a screening method. Each research question poses a new set of challenges that need to be considered when selecting an appropriate screening method. This flowchart is intended to provide some initial guidance for investigators embarking on a CRISPR-Cas9 functional genomics screen regarding the choice of model and the type of screens that may be employed to address the neurological disease research question at hand

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