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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

Fig. 6

Correlation between mouse strains and 30 AMP-AD modules. Pearson correlation coefficients between 30 human AMP-AD modules and mouse strains. AMP-AD modules are grouped into five previously-identified consensus clusters describing the major functional groups of AD-related alterations. The vertical axis represents AMP-AD modules and the horizontal axis represents mouse strains. Positive correlations are shown in blue and negative correlations in red color. Color intensity and size of the circles are proportional to the correlation coefficient. Correlations with adjusted p-value > 0.05 are considered non-significant and not included

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