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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

Fig. 5

rAAV-mediated expression of mIL6 and mIL10 in vivo. Media containing either rAAV2/8-3Y-EGFP, mIL6, or mIL10 was injected directly into each lateral ventricle of non-transgenic mice at P0. (a) Representative brain sections from mice aged P30 stained with an anti-IBA1 antibody to assess microgliosis (a) or an anti-GFAP antibody to assess astrogliosis (b). Brains injected with media containing no rAAV or rAAV2/8-3Y-EGFP were used as controls. Bar, 500 μm (hemi-brain) or 100 μm (10X magnification)

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Molecular Neurodegeneration

ISSN: 1750-1326