Fig. 3
From: Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue
Semi-quantitative analysis of 3H-PiB, 3H-THK5117 autoradiography and Amylo-Glo and AT8 staining. Box plot with a line at the median represent: a: Specific binding of 3H-PIB and for AD, DS and CN in HIPP and MFG. b: Amylo-Glo density for AD, DS and CN in HIPP and MFG. c: Specific binding of 3H-THK5117 for AD, DS and CN in HIPP and MFG. d: AT8 density for AD, DS and CN in HIPP and MFG. Specific binding for 3H-PIB and 3H-THK5117 is represented in fmol/mg. Gray matter was delineated manually using multigauge software. Density values for Amylo-Glo and AT8 are presented in b and d respectively. The red dots in each plot represent two DS-MCI cases. The empty blue circles in AD represent the EOAD