Fig. 10

White matter density, assessed by myelin basic protein (MBP) immunostaining, decreases in ipsi- and contralateral striatum of pMCAo mice, diabetic or not. a Schematic representation of a coronal brain section showing the infarct region, the striatum and regions (red boxes) from which white matter density was estimated. b MBP immunostaining in the ipsilateral striatum of a pMCAo+D mouse, scale bar: 500 μm. c In the ipsilateral striatum, MBP+ cell density was significantly lower in pMCAo+D mice than in C (P < 0.0001) or D mice (P < 0.01) and lower in pMCAo mice than in C mice (P < 0.001). d MBP+ cell density in contralateral striatum was significantly lower in pMCAo+D mice than C (P < 0.001) or D mice (P < 0.01) and lower in pMCAo mice than in C mice (P < 0.01). **P < 0.01, ***P < 0.001, ****P < 0.0001