Table 1 Demographic and Clinical Details of Subjects

Number of Subjects

56

55

Sex (% Male)

48.21

52.73

0.706

Age at stool collection (mean ± SD)

66.38 ± 6.73

67.63 ± 5.21

0.293

Body Mass Index (mean ± SD)

26.7 ± 3.56

27.63 ± 4.74

0.261

History of TIA/ischemic stroke (%)

37.50

5.56

<  0.001

Medication: ACE-inhibitor or AT1 antagonist (% yes)

48.21

29.09

0.051

Medication: calcium channel blocker (% yes)

19.64

5.45

0.042

Medication: statin (% yes)

48.21

18.18

0.001

Levodopa equivalent daily dose (LEDD mg; mean ± SD)

0 ± 0

608.61 ± 301.46

<  0.001

Non-Motor Symptoms Scale (NMSS) total (mean ± SD)

7.09 ± 6.35

48.36 ± 36.55

<  0.001

Rome III constipation subscore (items 9–15; mean ± SD)

2.46 ± 3.16

7.45 ± 5.22

<  0.001

Rome III irritable bowel syndrome criteria fulfilled (%)

7.14

36.36

<  0.001