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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: “Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies

Fig. 2

Tau pathological inclusions associated with neurodegenerative diseases stained with antibodies specific for p-tau. Neurofibrillary tangles (A) and neuritic plaques (B) in AD stained with antibody AT8 that reacts with tau phosphorylated at Ser202 and Thr205. Tufted astrocytes (C) in PSP stained with antibody AT8. Antibody 3G12 specific for tau phosphorylated at Ser208 depicts neurofibrillary tangles (D) and neuritic plaques (E, asterisks) in AD. Astrocytic plaques (F) in CBD stained with antibody AT8. Scale bar = 60 μm

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Molecular Neurodegeneration

ISSN: 1750-1326