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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration

Fig. 5

Granulins F levels in FTLD-TDP-Pgrn subjects versus controls. a, Western blot analysis of endogenous PGRN and Gran-F in IOC and MFG regions of control human brain. b, Quantification of PGRN and Gran-F levels in IOC and MFG regions in control subjects (ns, not significant). c, Western blot analysis of endogenous PGRN and Gran-F in IOC and MFG regions of FTLD-TDP-Pgrn subjects. d, Quantification of PGRN and Gran-F levels in IOC and MFG regions in FTLD-TDP-Pgrn subjects (*, p = 0.03). Error bars represent mean with standard deviation. Paired student-t test was performed between each pair. Sample numbers listed below each Western blot correspond to subject number in Table 2

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Molecular Neurodegeneration

ISSN: 1750-1326