Fig. 7

Cellular location and expression of AGO2 mRNA and mir-124-3p targets derived from publicly available scRNA-seq data. (A) t-SNE plot showing 19 retinal cell populations ascribed to a major class of retinal cell types indicated by colour-coding. Value between parentheses show the number of cells within each cluster. Colour coding applies to all subsequent plots in this Fig. (B) AGO2 expression levels across all cells with AGO2 expression > 0. Areas enclosed by dashed lines indicate the predominant cell population occupying that region of the t-SNE plot identified according to the colour-coding depicted in A. (C) AGO2 expression for each cell class depicted in ii represented as box plots showing the median values, Q1 (25th) and Q3 (75th⁾ quartiles. Whiskers extend 1.5 times above and below and interquartile range. Each point corresponds to the expression of a single cell within that cluster