Table 2 Clinical features of the enrolled patients
Clinical diagnosis | Bradykinesia | Rigidity | Tremor | Postural instability | Gait freezing | RBD | Early gait ataxia (3 years of onset) | Gait ataxia | Limb ataxia | Cerebellar Dysartria | Cerebellar Oculomotor disfunction | Hyposmia | Autonomic failure | Orthostatic Hypotension | Other cardiovascular dysautonomic symptoms | Urinary disfunction | Other dysautonomia |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PD_1 | + | + | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
PD_2 | + | + | + | – | – | + | – | – | – | – | – | – | – | – | + | + | + |
PD_3 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | + | – |
PD_4 | – | – | – | – | – | – | – | – | – | – | – | – | + | + | + | – | – |
PD_5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | + | + |
PD_6 | + | + | + | – | + | + | – | – | – | – | – | + | + | + | + | + | – |
PD_7 | + | + | + | – | – | – | – | – | – | – | – | + | – | – | – | – | + |
PD_8 | + | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
PD_9 | + | + | – | – | – | – | – | – | – | – | – | + | – | – | – | – | – |
PD_10 | + | + | – | + | – | – | – | – | – | – | – | – | + | + | + | + | + |
PD_11 | + | + | + | – | – | – | – | – | – | – | – | + | + | – | – | + | – |
PD_12 | + | + | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – |
PD_13 | + | + | + | – | + | – | – | – | – | – | – | – | + | – | – | + | + |
MSA-P_1 | + | + | + | + | – | – | + | + | + | + | – | – | + | + | + | + | + |
MSA-P_2 | + | + | + | + | – | – | – | – | – | – | – | – | + | – | + | + | + |
MSA-P_3 | + | + | + | + | – | + | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_4 | + | + | + | + | + | + | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_5 | + | + | – | + | – | + | – | + | + | + | – | – | + | + | + | + | + |
MSA-P_6 | + | + | + | + | – | + | – | + | + | + | – | – | + | + | + | + | + |
MSA-P_7 | + | + | – | + | – | – | – | + | + | + | – | – | + | + | + | + | + |
MSA-P_8 | + | + | + | + | – | – | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_9 | + | + | + | + | – | + | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_10 | + | + | + | – | – | + | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_11 | + | – | – | + | + | – | – | + | – | – | – | – | + | + | + | + | + |
MSA-P_12 | + | + | + | + | – | + | – | – | – | – | – | – | + | – | + | + | + |
MSA-P_13 | + | + | + | + | – | + | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_14 | + | + | + | + | – | + | – | – | – | – | – | + | + | + | + | + | + |
MSA-P_15 | + | + | + | + | – | + | – | – | – | – | – | – | + | – | + | + | + |
MSA-P_16 | + | + | + | + | – | – | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_17 | + | + | + | + | – | – | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_18 | + | + | – | + | – | – | – | – | – | + | – | – | + | – | + | + | + (sudomotor) |
MSA-P_19 | + | + | – | + | – | – | – | – | – | – | – | – | + | + | + | + | + |
MSA-P_20 | + | + | – | + | – | – | – | + | + | + | – | – | + | – | + | + | + |
MSA-C_1 | + | + | – | + | – | + | + | + | + | + | – | – | + | + | + | + | + (stipsi) |
MSA-C_2 | – | – | – | – | – | – | + | + | + | + | – | + | + | – | + | – | – |
MSA-C_3 | + | – | – | – | – | + | + | + | + | + | + | – | + | – | + | + | + (stipsi) |
MSA-C_4 | – | + | – | + | – | – | + | + | + | + | + | + | + | – | + | + | + (stipsi) |
MSA-C_5 | + | – | – | + | – | + | + | + | + | + | + | – | + | – | + | + | + (sudomotor) |
MSA-C_6 | + | + | – | + | – | – | + | + | + | + | + | – | + | – | + | + | + (genital) |
MSA-C_7 | – | – | – | + | – | + | + | + | + | + | + | – | + | – | + | – | – |
MSA-C_8 | + | – | – | + | – | + | + | + | + | + | + | – | + | + | + | + | + |
MSA-C_9 | – | – | – | + | – | – | + | + | + | + | + | – | – | – | – | – | + |
MSA-C_10 | + | – | – | + | – | + | + | + | + | + | + | – | + | + | + | + | + |