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Table 1. Brain samples used in this study

From: Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity

Brain ID

Category

Age

Sex

PMI

Assay

BWH04

LP-NCI

53

M

ND

MEA

MGH2038

LP-NCI

78

F

6

MEA

MGH1887

LP-NCI

60

M

ND

MEA

MGH2018

LP-NCI

92

F

24

MEA

RM100

LP-NCI

88

M

9

NI

RM105

LP-NCI

75

F

3

NI

RM106

LP-NCI

91

F

15

NI

BWH02

LP-NCI

76

F

ND

MEA

MGH1837

LP-NCI

68

M

27

MEA

MGH2068

LP-NCI

79

F

9

MEA

RM101

LP-NCI

76

M

5

NI

RM102

LP-NCI

82

M

6

NI

RM103

LP-NCI

85

M

8

NI

RM104

LP-NCI

79

F

18

NI

RM207

HP-NCI

89

F

17

NI

RM205

HP-NCI

83

F

6

NI

RM208

HP-NCI

80

F

5

MEA / NI

MGH1846

HP-NCI

92

M

ND

MEA

RM201

HP-NCI

78

F

24

NI

RM206

HP-NCI

85

F

12

NI

RM200

HP-NCI

86

M

7

NI

BWH03

HP-NCI

77

M

ND

MEA

MGH1965

HP-NCI

76

F

48

MEA

BWH01

HP-NCI

76

F

ND

MEA

RM202

HP-NCI

88

F

12

NI

RM204

HP-NCI

82

F

8

NI

RM203

HP-NCI

86

F

13

NI

RM209

HP-NCI

87

F

15

NI

MGH1892

AD

67

M

28

MEA

RM304

AD

87

F

5

MEA / NI

MGH2031

AD

70

F

8

MEA

RM301

AD

81

M

12

NI

RM305

AD

87

F

10

MEA / NI

ALB01

AD

68

F

18

MEA / NI

MGH2037

AD

73

F

22

MEA

MGH2039

AD

74

M

24

MEA

RM303

AD

87

F

17

NI

RM306

AD

90

F

5

NI

RM302

AD

89

M

4

NI

RM307

AD

91

F

7

NI

RM308

AD

98

F

7

NI

MGH1168

AD

89

F

ND

NA

RM300

AD

85

M

5

NI

  1. Postmortem prefrontal cortex was acquired from 43 individuals. Listed are category, age at death, postmortem interval (PMI), sex, and assay(s) in which the samples were used. Due to limited supply brain tissue for many of the samples, most were used in only 1 of the 2 assays.
  2. Abbreviations: LP-NCI low pathology and non-cognitively impaired, HP-NCI high pathology and non-cognitively impaired, AD Alzheimer’s disease, ND not determined/not known, M male, F female, MEA multi-electrode array spontaneous activity assay, NI neurite integrity assay.