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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides

Fig. 6

BACE1 deficiency enhances P38, ERK1/2, and cJun phosphorylation. A Western blot of BACE1-null and WT primary astrocytes lysates. Images indicate major bands for pJun, total Jun, pP38, total P38, pERK1/2, pJNK and Calnexin. B Quantification of pJun/total cJun, pP38/total p38, and pERK1/2 band intensity normalized to Calnexin (N = 3, * p-value < 0.05, One-way ANOVA with Tukey post testing comparing between samples)

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