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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer’s disease and potential therapeutics

Fig. 1

Human astrocytes get dysfunctional at early stages of AD and exacerbate the pathology affecting major AD processes. Combination of hiPSC-based in vitro and in vivo models with gene editing, multi-omics technologies and high-resolution imaging will allow in depth analyses of human astrocytes in AD and enable the development of astrocyte targeting therapeutics. Created with BioRender.com

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