Fig. 6
From: Sex specific molecular networks and key drivers of Alzheimer’s disease
LRP10 Binding Partners. A Left: The design of the yeast two-hybrid system screening assays. Right: The summary table of eight positive hits that were identified and validated by β-galactosidase assays. B The interaction between LRP10 and its binding partner CD34, NBR1 or ACBD3 was detected by co-immunoprecipitation (co-IP) pull-down in female E4FAD mouse brains of LRP10 OE versus scramble controls. The amounts of total input (CD34, NBR1 and ACBD3) in mouse brain lysates were determined as well. C Cell type specific enrichment expression patterns of LRP10 and its binding partners (CD34, NBR1 and ACBD3) in female E4FAD mouse brains of LRP10 OE versus scramble controls