Fig. 3
From: The role of peripheral inflammatory insults in Alzheimer’s disease: a review and research roadmap
Roadmap: Acute inflammatory events and Alzheimer’s disease To overcome prior barriers to progress in the immunity-AD field, longitudinal, multimodal appraisal of acute inflammatory events in diverse cohorts is needed. A proposed roadmap of studies needed to address gaps in the literature is depicted, focusing on biological, neuroimaging, and environmental assessments of the relationship between acute inflammatory exposures and long-term outcomes, as well as the development of interventional trials aimed at resolving systemic inflammation