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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores

Fig. 1

Locus Zoom plots showing the association of SNPs in the regions of novel loci with cognitive domains. The SNP with the lowest p-value at each locus is indicated with a purple diamond. Computed estimates of linkage disequilibrium (r2) of SNPs in the region with top-ranked SNP are color-coded according to the key. Vertical blue lines indicate locations of high recombination rates. Locations of genes in the region are shown below the diagram. a Association of rs157405 with executive function in the community-based cohorts. b Association of rs705353 with language in the clinic-based cohorts. c Association of rs117523305 with memory in the community-based cohorts. d Association of rs145012974 with language in the total sample. e Association of rs5848 with memory in the total sample

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Molecular Neurodegeneration

ISSN: 1750-1326