Fig. 2
Locus Zoom plots showing genome-wide significant pleiotropy for SNPs in the regions of novel loci. The SNP with the lowest p-value at each locus is indicated with a purple diamond. Computed estimates of linkage disequilibrium (r2) of SNPs in the region with top-ranked SNP are color-coded according to the key. Vertical blue lines indicate locations of high recombination rates. Locations of genes in the region are shown below the diagram. a Association of rs12447050 with executive function and memory in the community-based cohorts. b Association of rs56162098 with language and memory in the community-based cohorts. c Association of rs145989094 with executive function and memory in the community-based cohorts. d Association of rs145989094 with language and memory in the community-based cohorts. e Association of rs73005629 with language and memory in the clinic-based cohorts