Table 1 Study cohort characteristics
From: TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains
Study group | N | Age of death (yrs) | N females (%) | Braak | Thal | Duration (yrs) | Age of onset (yrs) |
|---|---|---|---|---|---|---|---|
Cognitively normal (CN) | 27 | 79 (54, 95) | 10 (37%) | II (0, IV) | 0 (0, 3) | NA | NA |
AD no TDP | 27 | 78 (59, 89) | 11 (40.7%) | VI (V, VI) | 5 (4, 5) | 9 (1, 14) | 70 (54, 84) |
AD-TDP | 71 | 84 (62, 101) | 47 (66.2%) | VI (IV, VI) | 5 (3, 5) | 10 (3, 23) | 73 (51, 94) |
AD TDP type α | 36 | 86 (68, 101) | 21 (58.3%) | VI (IV-V, VI) | 5 (3, 5) | 9 (3, 18) | 73 (60, 94) |
AD TDP type β | 35 | 83 (62, 92) | 26 (76.5%) | VI (IV, VI) | 5 (3, 5) | 10.5 (3, 23) | 72 (51, 87) |
FTLD-TDP | 67 | 71 (45, 91) | 32 (47.8%) | I-II (0, IV-V) | 1 (0, 5) | 5 (1, 25) | 64 (42, 90) |
FTLD-TDP type A | 32 | 77 (51, 91) | 16 (50%) | I (0, III-IV) | 1 (0, 5) | 6 (1, 25) | 68 (47, 90) |
FTLD-TDP type B | 35 | 72 (45, 87) | 16 (45.7%) | I-II (0, IV-V) | 0.5 (0, 5) | 4 (1, 20) | 63 (42, 82) |