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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer’s disease with multi-modal PET and plasma GFAP

Fig. 3

Cross-sectional correlation analyses between 11C-DED PET binding and plasma GFAP levels. (A-B) Scatterplots evaluating the relationship between 11C-DED PET binding and plasma GFAP levels in carriers of ADAD mutations and patients with sporadic Alzheimer’s disease for composite temporal ROIs, and (C) surface maps illustrating in colour the cortical ROIs with a significant cross-sectional association between 11C-DED PET binding and plasma GFAP. The Spearman’s correlation coefficient (rho), the p and power values are shown. NC: non-carriers; pMC: presymptomatic mutation carriers; sMC: symptomatic mutation carriers; MCI+: MCI with a positive amyloid-β PET scan; AD: Alzheimer’s disease dementia

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Molecular Neurodegeneration

ISSN: 1750-1326