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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Fig. 3

Engagement of CD169+ perivascular macrophages with vascular amyloid immune complex in 3D6 treated hTau APP KI Mice. (a-d) Four-color immunofluorescence of amyloid (X-34, blue), antibody (IgG or 3D6, green), laminin (red) and perivascular macrophage (CD169, cyan) in hTau APP KI mice treated with biotinylated 3D6 or IgG control. X-34, antibody, laminin and CD169 immunoreactivity overlay (Merge). Scale bar 3 μm merge or 2 μm inset, respectively

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Molecular Neurodegeneration

ISSN: 1750-1326