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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus

Fig. 6

Rs1990622 affects the degree of unsaturation in phosphatidylethanolamine (PE) and PE plasmalogen (PEp). PE and PEp levels as a function of the number of double bonds in the acyl chains, grouped by rs1990622 genotype (APOE ε3/ε3 genotype only; NG/G=9, NA/G=20, NA/A=15). Statistical significance was determined by ANOVA with Tukey’s post-hoc test: *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Neurodegeneration

ISSN: 1750-1326