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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Regulation of the hippocampal translatome by Apoer2-ICD release

Fig. 3

Synaptic effects of overexpressing either Apoer2-ICD in Apoer2WT. A, B Schematic representation of the experiment. C Diagram depicting the up- (purple symbols) and down- (yellow symbols) regulated transcripts by both ICDs in the same direction (circles), ICD[+19] (plus-sign) or ICD[Δ19] (triangles). D Heatmap of the log2FC differentially-transcribing transcripts in Apoer2WT with either Apoer2-ICD from the network in Fig. 1F. Heatmap displaying the log2FC expression of the synaptic transcripts not represented in the networks in Panels A and B, respectively. *p<0.05, **p<0.01

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