Table 2 Characterization of human cases used for stereotactical injection. NA = non-applicable
From: TDP-43 pathology is associated with increased tau burdens and seeding
Neuropathological Diagnosis | Injection group | Age | Sex | Aβ phase | Braak NFT stage | LATE-NC stage | CERAD core | NIA-AA score | CDR score |
|---|---|---|---|---|---|---|---|---|---|
PART | Control | 76 | m | 0 | I | 0 | 0 | 1 | 1 |
ADNC | AD(LATE-NC-) | 54 | f | 5 | VI | 0 | 2 | 3 | 3 |
ADNC, LATE-NC | AD(LATE-NC+) | 74 | m | 5 | VI | 2 | 2 | 3 | 2 |
FTLD-TDP type C | FTLD-TDP | 62 | f | 0 | 0 | NA | 0 | 0 | 3 |