Table 3 Experimental mouse groups with respective protein concentrations which have been stereotactically injected. Injection volume = 2,5µL
From: TDP-43 pathology is associated with increased tau burdens and seeding
Group | Total protein (µg/mL) | Total protein per site (µg) | p-tau181 (pg/mL) | p-tau199 (pg/mL) | p-tau181 per site (pg) | p-tau199 per site (pg) | Total TDP-43 (ng/mL) | TDP-43 per site (pg) |
|---|---|---|---|---|---|---|---|---|
Control | 582 | 1,46 | 186,54 | 13,10 | 0,47 | 0,03 | 113,82 | 284,55 |
AD (LATE-NC-) | 700 | 1,75 | 34198,23 | 6946,48 | 85,50 | 17,37 | 1482,12 | 3705,30 |
AD (LATE-NC +) | 826 | 2,07 | 177256,20 | 17700,70 | 443,14 | 44,25 | 1157,58 | 2893,95 |
FTLD-TDP | 1220 | 3,05 | 4022,57 | 180,91 | 10,06 | 0,45 | 3637,94 | 9094,85 |