Table 1 Summary of amyloid fibril associated proteins that have been previously found at amyloid plaques or with Aβ peptides

Heterogeneous ribonucleoproteins

HNRNPA2B1, HNRNPH1

M, H, T, D, N, F

MS

[63]

Serine proteases

PRSS1

M, H, T, D, N

IHC

[64]

14–3-3 proteins

YWHAB, YWHAG, YWHAQ, YWHAZ, SFN

M, H, T, D, N

MS, BC

[65,66,67,68]

Ribosomal large subunits

RPL11, UBA52

M, H, T, D, F

BC, MS

[63, 66]

Cofilin-1

CFL1

H, T, D, N

MS

[63]

Elongation factor 1-alpha 1

EEF1A1

M, T, D, N

MS

[63, 69]

Heat shock protein 90 family proteins

HSP90AB1

T, D, N, F

IHC, MS

[65, 70]

Heat shock protein 70 family proteins

HSPA8, HSPA1L

M, T, D, N

MS

[63, 66, 69]

Succinate dehydrogenase flavoprotein

SDHA

H, T, D, N

MS

[70]

Aconitate hydratase

ACO2

T, D, N

MS

[70]

Actin, cytoskeletal proteins

ACTA1, ACTA2, ACTG2

M, H, T

IHC, MS

[59, 66, 70]

Amyloid-beta precursor protein

APP

M, H, T

IHC, BC, MS

[2, 70]

Na + /K + transporting ATPase subunits

ATP1A3

M, T, N

IHC, MS

[66, 70, 71]

Calcium-transporting ATPase 1, ER

ATP2A2

T, D, N

IHC

[72]

Calmodulin-1, -2

CALM1, CALM2

H, T, D

IHC, BC, MS

[66, 73]

CaMKII subunits

CAMK2A

M, T, N

IHC, MS

[63, 70, 74]

Clathrin heavy chain 1

CLTC

T, D, N

MS

[66, 70]

Dihydropyrimidinase-related proteins

CRMP1, DPYSL2, DPYSL3

T, D, N

MS

[66]

Dynamin-1

DNM1

T, D, F

MS

[63, 65, 70]

Desmoplakin

DSP

M, H, T

MS

[75]

Dyneins, motor proteins

DYNC1H1

T, N, F

IHC, MS

[60, 63, 65]

Glyceraldehyde-3-phosphate dehydrogenase

GAPDH

T, D, N

MS

[63]

Glutamine synthetase

GLUL

T, D, N

MS

[70]

Guanine nucleotide-binding protein subunits

GNAO1, GNB1, GNB2

T, D, N

MS

[70]

Alpha-internexin

INA

T, D, N

IHC, MS

[61, 66, 70]

Malate dehydrogenase 2

MDH2

T, D, N

MS

[66]

Vesicle-fusing ATPase

NSF

T, D, N

MS

[70]

Pyruvate dehydrogenase E1

PDHB

T, D, N

MS

[70, 76]

Phosphoglycerate kinase

PGK1

H, T, N

MS

[63, 75]

Pyruvate kinase

PKM

T, D, N

MS

[70]

Peroxiredoxins

PRDX6

T, D, F

MS

[66]

Ribosomal small subunits

RPS20

H, D, F

MS

[63]

Excitatory amino acid transporter 2

SLC1A2

M, T, D

MS

[70]

Synaptosomal-associated protein 25

SNAP25

T, D, N

IHC, MS

[32, 63, 70]

Clathrin coat assembly protein AP180

SNAP91

H, T, N

IHC, MS

[32, 66]

Spectrin alpha chain

SPTAN1

T, D, F

IHC, MS

[59, 70]

Thioredoxin

TXN

M, H, T

MS

[77]

Polyubiquitin-B

UBB, UBC

M, H, T

IHC, MS

[63, 66, 78]

Ubiquitin C-terminal hydrolase L1

UCHL1

H, T, N

BC

[79]

Voltage-dependent anion channel 1, 2

VDAC1, VDAC2

M, T, D

IHC, BC, MS

[63, 80]

Vimentin

VIM

T, D, N

IHC, MS

[63, 65, 69, 81]