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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: cGAS-STING triggers inflammaging-associated neurodegeneration

Fig. 1

cGAS-STING pathway leads to inflammation and microglia-dependent neurodegeneration. Overview of murine brain aging, homeostatic and activated microglia, induction of mitochondrial DNA leakage-dependent cGAS-STING pathway, synthesis of type I IFN and proinflammatory cytokines during loss of homeostasis, leading to neurodegeneration

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Molecular Neurodegeneration

ISSN: 1750-1326