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Table 3 Correlations between age and protein levels in mutation carriers

From: Altered plasma protein profiles in genetic FTD – a GENFI study

Protein

p-value

β

RPH3A

9.98 × 10–7

0.019 (0.013—0.026)

IL1B

2.16 × 10–4

0.012 (0.006—0.017)

RGS7BP

5.35 × 10–4

0.012 (0.006—0.018)

TFEB

5.35 × 10–4

0.013 (0.006—0.019)

S100A12

1.04 × 10–3

0.013 (0.006—0.02)

GLA

4.18 × 10–3

0.01 (0.004—0.016)

EIF4ENIF1

5.22 × 10–3

0.008 (0.003—0.014)

APOE

5.22 × 10–3

0.009 (0.003—0.015)

CHGA

5.22 × 10–3

0.009 (0.003—0.015)

LRRFIP2

5.22 × 10–3

0.011 (0.004—0.018)

ADAMTS1

5.25 × 10–3

0.009 (0.003—0.015)

LAMA2

2.15 × 10–2

0.008 (0.002—0.014)

APOC1

3.09 × 10–2

0.006 (0.001—0.011)

XPO5

1.19 × 10–1

0.006 (-0.001—0.013)

LCAT

1.57 × 10–1

0.005 (-0.002—0.012)

NPTX2

1.68 × 10–1

0.005 (-0.002—0.013)

C7

3.73 × 10–1

0.003 (-0.003—0.008)

  1. Correlations between protein levels and age in all mutation carriers (MC) including p-values and beta coefficients with 95% confidence intervals. All p-values are adjusted for multiple testing. Non-significant p-values are in italics