Fig. 2

Detailed schematic of microglial protein functions in Alzheimer’s disease pathology. The relationships between key microglial gene products with pathology-related pathways affected in Alzheimer’s disease are indicated. The colour shading of protein names indicates the abundance of the corresponding transcripts in human myeloid cells relative to all brain cells (quantified by single-cell RNAseq [36]). Numbers indicate cited references that support the functional associations depicted in the schematics. Created with BioRender.com