Table 1 Blood-based lipid biomarkers of APOECh carriers and noncarriers
From: Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants
EUR Carriers (N=36) | EUR Noncarriers (N=129,240) | KS test | |||
|---|---|---|---|---|---|
Min, Max | Median | Min, Max | Median | ||
Apolipoprotein A | 1.03-2.12 | 1.64 | 0.52-2.50 | 1.55 | D=0.19 P-value=0.239 |
Apolipoprotein B | 0.65-1.37 | 0.88 | 0.40-1.99 | 1.02 | D=0.31 P-value=0.004 |
Apolipoprotein B (statin adjusted) | 0.65-1.37 | 0.94 | 0.40-2.76 | 1.06 | D=0.25 P-value=0.036 |
C reactive protein | 0.09-16.48 | 1.12 | 0.08-78.26 | 1.32 | D=0.12 P-value=0.662 |
Cholesterol | 3.82-7.83 | 5.32 | 1.71-12.50 | 5.73 | D=0.18 P-value=0.263 |
Cholesterol (statin adjusted) | 3.82-7.83 | 5.80 | 1.88-15.56 | 5.91 | D=0.15 P-value=0.427 |
High-density lipoprotein | 0.80-2.05 | 1.56 | 0.23-4.19 | 1.47 | D=0.2 P-value=0.225 |
Low-density lipoprotein | 2.19-5.06 | 3.25 | 0.75-8.86 | 3.55 | D=0.23 P-value=0.072 |
Low-density lipoprotein (statin adjusted) | 2.23-5.06 | 3.36 | 0.80-12.96 | 3.70 | D=0.21 P-value=0.119 |
Lipoprotein A | 4.10-178.95 | 22.00 | 3.80-189.00 | 20.50 | D=0.11 P-value=0.838 |
Triglycerides | 0.79-6.31 | 1.71 | 0.23-11.15 | 1.42 | D=0.16 P-value=0.329 |